The human cytomegalovirus 80-kilodalton but not the 72-kilodalton immediate-early protein transactivates heterologous promoters in a TATA box-dependent mechanism and interacts directly with TFIID.

We have asked how the human cytomegalovirus major immediate-early 1 (IE1) and 2 (IE2) proteins act to transactivate heterologous cellular and viral promoters. Here we show that transactivation of the human immunodeficiency virus long terminal repeat and the 70,000-molecular-weight heat shock protein...

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Detalhes bibliográficos
Main Authors: Hagemeier, C, Walker, S, Caswell, R, Kouzarides, T, Sinclair, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC241253/
https://ncbi.nlm.nih.gov/pubmed/1318414
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