Antibody C219 recognizes an α-helical epitope on P-glycoprotein
The ABC transporter, P-glycoprotein, is an integral membrane protein that mediates the ATP-driven efflux of drugs from multidrug-resistant cancer and HIV-infected cells. Anti-P-glycoprotein antibody C219 binds to both of the ATP-binding regions of P-glycoprotein and has been shown to inhibit its ATP...
Na minha lista:
| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1999
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24124/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10570132/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.24.13679 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|