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The pathogenesis of infection with minute virus of mice depends on expression of the small nonstructural protein NS2 and on the genotype of the allotropic determinants VP1 and VP2.

Neonatal C3H/He mice were oronasally inoculated with similar doses of four genotypes of minute virus of mice (MVM). MVMp, a fibroblast-specific variant, caused an asymptomatic infection. MVM(1035), a chimera which had the allotropic determinant of virulent MVMi inserted onto an MVMp background, caus...

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Udgivet i:J Virol
Principais autores: Brownstein, D G, Smith, A L, Johnson, E A, Pintel, D J, Naeger, L K, Tattersall, P
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241074/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1373202/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.5.3118-3124.1992
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