5-Azacytidine and RNA secondary structure increase the retrovirus mutation rate.

A broad spectrum of mutations occurs at a high rate during a single round of retrovirus replication (V.K. Pathak and H. M. Temin, Proc. Natl. Acad. Sci. USA 87:6019-6023, 1990). We have now determined that this high rate of spontaneous mutation can be further increased by 5-azacytidine (AZC) treatme...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	J Virol
Päätekijät:	Pathak, V K, Temin, H M
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology (ASM) 1992
Aiheet:	Research Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241071/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1373201/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.5.3093-3100.1992
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