Infection of HeLa cells with poliovirus results in modification of a complex that binds to the rRNA promoter.

In HeLa cells, RNA polymerase I (Pol I)-mediated transcription is severely inhibited soon after infection with poliovirus. We have developed a gel retardation assay to analyze DNA-protein complexes formed at the Pol I promoter. We show here that two complexes (A and C) formed by nuclear extracts fro...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Rubinstein, S J, Hammerle, T, Wimmer, E, Dasgupta, A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241067/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1313918/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.5.3062-3068.1992
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