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3-D structure of extracellular matrix regulates gene expression in cultured hepatic stellate cells to induce process elongation
HSCs showed myofibroblast-like shapes when cultured on polystyrene surface or on type I collagen-coated surface, whereas HSCs cultured on type I collagen gel were induced to elongate cellular processes, suggesting that HSCs recognize 3-D structure of extracellular type I collagen fibrils and change...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2410227/ https://ncbi.nlm.nih.gov/pubmed/14960156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-5926-2-S1-S4 |
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