Tumour-derived TGF-β1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cells

The development of an altered stromal microenvironment is a common feature of many tumours including squamous cell carcinoma (SCC), and there is increasing evidence that these changes in the stroma, which include increased expression of proteases and cytokines, may actually promote tumour progressio...

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Detalhes bibliográficos
Main Authors: Lewis, M P, Lygoe, K A, Nystrom, M L, Anderson, W P, Speight, P M, Marshall, J F, Thomas, G J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Molecular and Cellular Pathology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2410183/
https://ncbi.nlm.nih.gov/pubmed/14970860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601611
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