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Identification and characterisation of constitutional chromosome abnormalities using arrays of bacterial artificial chromosomes

Constitutional chromosome deletions and duplications frequently predispose to the development of a wide variety of cancers. We have developed a microarray of 6000 bacterial artificial chromosomes for array-based comparative genomic hybridisation, which provides an average resolution of 750 kb across...

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Detalhes bibliográficos
Main Authors: Cowell, J K, Wang, Y D, Head, K, Conroy, J, McQuaid, D, Nowak, N J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2410171/
https://ncbi.nlm.nih.gov/pubmed/14970865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601588
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