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Cellular responses to ionising radiation of AT heterozygotes: differences between missense and truncating mutation carriers
It has been estimated that approximately 1% of the general population are ataxia telangiectasia (AT) mutated (ATM) heterozygotes. The ATM protein plays a central role in DNA-damage response pathways; however, the functional consequences of the presence of either heterozygous truncating or missense m...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2410162/ https://ncbi.nlm.nih.gov/pubmed/14970866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601549 |
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