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On the effects of topical synthetic pseudoceramides: comparison of possible keratinocyte toxicities provoked by the pseudoceramides, PC104 and BIO391, and natural ceramides

BACKGROUND: Ceramides (Cer) in the stratum corneum are essential for epidermal permeability barrier function. Thus, topical Cer replacement therapy has been employed to improve barrier function in clinical situations associated with Cer deficiency, e.g., atopic dermatitis. Because of the disadvantag...

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Autors principals: Uchida, Yoshikazu, Holleran, Walter M., Elias, Peter M.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2410086/
https://ncbi.nlm.nih.gov/pubmed/18396015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jdermsci.2008.02.007
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