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Intracellular angiotensin II directly induces in vitro transcription of TGF-β1, MCP-1 and NHE-3 mRNAs in isolated rat renal cortical nuclei via activation of nuclear AT(1) receptors

The present study tested the hypothesis that intracellular angiotensin II (Ang II) directly induces transcriptional effects by stimulating AT(1) receptors in the nucleus of rat renal cortical cells. Intact nuclei were freshly isolated from the rat renal cortex and transcriptional responses to Ang II...

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Autori principali: Li, Xiao C., Zhuo, Jia L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2410035/
https://ncbi.nlm.nih.gov/pubmed/18256274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00432.2007
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