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Neuroleptics and animal models: feasibility of oral treatment monitored by plasma levels and receptor occupancy assays

The administration of neuroleptics in animal models has been extensively reported and plays an important role in the study of schizophrenia. Our study was designed to address the following questions: (1) Is it possible to achieve steady-state receptor occupancy levels administering neuroleptics in d...

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Detalhes bibliográficos
Main Authors: Perez-Costas, Emma, Guidetti, Paolo, Melendez-Ferro, Miguel, Kelley, Joyce J., Roberts, Rosalinda C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2410030/
https://ncbi.nlm.nih.gov/pubmed/18193153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00702-007-0004-5
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