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Analysis of resveratrol as a lung cancer chemopreventive agent in A/J mice exposed to benzo[a]pyrene

Resveratrol inhibits PAH bioactivation through reduced expression of the CYP1A1 and CYP1B1 genes in human bronchial epithelial cells. Ad libitum access to a diet containing resveratrol showed no effect on benzo[a]pyrene-induced lung tumorigenesis in A/J mice. Also, resveratrol did not change CYP1A1...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Berge, G, Øvrebø, S, Eilertsen, E, Haugen, A, Mollerup, S
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409901/
https://ncbi.nlm.nih.gov/pubmed/15316568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602125
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