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Thymidylate synthase predictive power is overcome by irinotecan combination therapy with S-1 for gastric cancer

The predictive values of thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) gene expressions were retrospectively evaluated in patients with gastric cancer treated by a regimen containing S-1. The study population consisted of 53 patients registered into different two phase II studi...

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Main Authors: Ichikawa, W, Takahashi, T, Suto, K, Yamashita, T, Nihei, Z, Shirota, Y, Shimizu, M, Sasaki, Y, Hirayama, R
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409894/
https://ncbi.nlm.nih.gov/pubmed/15354215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602139
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