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Clinical significance of Caveolin-1, Caveolin-2 and HER2/neu mRNA expression in human breast cancer

Caveolin-1 and -2 (CAV1, CAV2) are closely linked genes localised to the fragile region of 7q31 (FRA7G), and loss of heterozygosity involving this region has been reported in breast cancer. Several studies have suggested that CAV1 is a negative regulator of HER2/neu signal transduction in vitro. How...

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Detalhes bibliográficos
Main Authors: Sagara, Y, Mimori, K, Yoshinaga, K, Tanaka, F, Nishida, K, Ohno, S, Inoue, H, Mori, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409871/
https://ncbi.nlm.nih.gov/pubmed/15305200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602029
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