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Nuclear survivin as a biomarker for non-small-cell lung cancer

Survivin inhibits apoptosis and promotes mitosis. We determined whether nuclear or cytoplasmic localisation of survivin predicts survival of 48 patients with resected non-small-cell lung cancer (NSCLC). Patients with nuclear staining of survivin had significantly worse survival (relative risk: 3.9,...

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Detalhes bibliográficos
Main Authors: Lu, B, Gonzalez, A, Massion, P P, Shyr, Y, Shaktour, B, Carbone, D P, Hallahan, D E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409840/
https://ncbi.nlm.nih.gov/pubmed/15266313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602027
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