Genetic alterations and protein expression of KIT and PDGFRA in serous ovarian carcinoma

KIT and PDGFRA are receptor tyrosine kinases that can be specifically inactivated by small-molecule tyrosine kinase inhibitors, notably imatinib mesylate. In ovarian carcinoma, expression of KIT and PDGFRA protein has been documented, but the frequency and the molecular background of expression are...

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Autori principali: Lassus, H, Sihto, H, Leminen, A, Nordling, S, Joensuu, H, Nupponen, N N, Butzow, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2004
Soggetti:
Molecular and Cellular Pathology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409787/
https://ncbi.nlm.nih.gov/pubmed/15583695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602252
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