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Genomic imbalances in 70 snap-frozen cervical squamous intraepithelial lesions: associations with lesion grade, state of the HPV16 E2 gene and clinical outcome

Host genomic abnormalities may determine the natural history of cervical squamous intraepithelial lesions (SILs). We undertook comparative genomic hybridisation analysis of epithelium carefully microdissected from 70 cervical SILs, the largest series to date. In contrast to previous studies, we used...

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Detalhes bibliográficos
Main Authors: Alazawi, W, Pett, M, Strauss, S, Moseley, R, Gray, J, Stanley, M, Coleman, N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409784/
https://ncbi.nlm.nih.gov/pubmed/15545968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602237
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