Overexpression of P70 S6 kinase protein is associated with increased risk of locoregional recurrence in node-negative premenopausal early breast cancer patients

The RPS6KB1 gene is amplified and overexpressed in approximately 10% of breast carcinomas and has been found associated with poor prognosis. We studied the prognostic significance of P70 S6 kinase protein (PS6K) overexpression in a series of 452 node-negative premenopausal early-stage breast cancer...

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Detalhes bibliográficos
Main Authors: van der Hage, J A, van den Broek, L J C M, Legrand, C, Clahsen, P C, Bosch, C J A, Robanus-Maandag, E C, van de Velde, C J H, van de Vijver, M J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Molecular and Cellular Pathology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409704/
https://ncbi.nlm.nih.gov/pubmed/15083183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601741
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