Gene array of VHL mutation and hypoxia shows novel hypoxia-induced genes and that cyclin D1 is a VHL target gene

Gene expression analysis was performed on a human renal cancer cell line (786-0) with mutated VHL gene and a transfectant with wild-type VHL to analyse genes regulated by VHL and to compare with the gene programme regulated by hypoxia. There was a highly significant concordance of the global gene re...

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Detalhes bibliográficos
Main Authors: Wykoff, C C, Sotiriou, C, Cockman, M E, Ratcliffe, P J, Maxwell, P, Liu, E, Harris, A L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409644/
https://ncbi.nlm.nih.gov/pubmed/15026807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601657
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