Chimeric polioviruses that include sequences derived from two independent antigenic sites of foot-and-mouth disease virus (FMDV) induce neutralizing antibodies against FMDV in guinea pigs.

Five poliovirus recombinants containing sequences corresponding to foot-and-mouth disease virus (FMDV) antigenic sites were constructed. Viable virus was recovered from four of these plasmids, in which the VP1 beta B-beta C loop (antigenic site 1) of poliovirus type 1 Sabin had been replaced with se...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Kitson, J D, Burke, K L, Pullen, L A, Belsham, G J, Almond, J W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240962/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1709696/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.6.3068-3075.1991
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