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Low-dose interferon-γ-producing human neuroblastoma cells show reduced proliferation and delayed tumorigenicity
Interferon-γ (IFN-γ) directs T helper-1 cell differentiation and mediates antitumour effects in preclinical models. However, high-dose IFN-γ is toxic in vivo, and IFN-γ-transfected neuroblastoma (NB) cells secreting high amounts of the cytokine may be lost due to cell apoptosis or differentiation. T...
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| Asıl Yazarlar: | , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2004
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2409504/ https://ncbi.nlm.nih.gov/pubmed/15150552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601842 |
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