Simian virus 40 (SV40) small t antigen inhibits SV40 DNA replication in vitro.

We describe a biochemical function of simian virus 40 small t antigen, the inhibition of simian virus 40 large T antigen-mediated viral DNA replication in an in vitro replication system. Our results suggest that in this system, small t antigen prevents protein phosphatase 2A-mediated activation of l...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Carbone, M, Hauser, J, Carty, M P, Rundell, K, Dixon, K, Levine, A S
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1992
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240946/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1310784/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.3.1804-1808.1992
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