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High-fat diets cause insulin resistance despite an increase in muscle mitochondria

It has been hypothesized that insulin resistance is mediated by a deficiency of mitochondria in skeletal muscle. In keeping with this hypothesis, high-fat diets that cause insulin resistance have been reported to result in a decrease in muscle mitochondria. In contrast, we found that feeding rats hi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hancock, Chad R., Han, Dong-Ho, Chen, May, Terada, Shin, Yasuda, Toshihiro, Wright, David C., Holloszy, John O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409421/
https://ncbi.nlm.nih.gov/pubmed/18509063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802057105
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