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Precision-mapping and statistical validation of quantitative trait loci by machine learning
BACKGROUND: We introduce a QTL-mapping algorithm based on Statistical Machine Learning (SML) that is conceptually quite different to existing methods as there is a strong focus on generalisation ability. Our approach combines ridge regression, recursive feature elimination, and estimation of general...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2409372/ https://ncbi.nlm.nih.gov/pubmed/18452626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-9-35 |
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