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The Effect of Ethanol on the Release of Opioids from Oral Prolonged-Release Preparations

Recent experience has prompted the US FDA to consider whether ethanol ingestion may modify the release characteristics of prolonged-release formulations, where dose dumping may be an issue for patient safety. The influence of ethanol on the in vitro release of opioid drugs from some prolonged-releas...

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Detalhes bibliográficos
Main Authors: Walden, Malcolm, Nicholls, Fiona A., Smith, Kevin J., Tucker, Geoffrey T.
Formato: Artigo
Idioma:Inglês
Publicado em: Informa Healthcare 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409176/
https://ncbi.nlm.nih.gov/pubmed/17882730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/03639040701377292
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