Differential Effect of Low Dose Thiazides on the Renin Angiotensin System in Genetically Hypertensive and Normotensive Rats

Fifty years since their introduction, thiazide diuretics are established as first-line therapy in the treatment of hypertension. Because the dosing profile for thiazide agents lessened, the mechanism responsible for the blood pressure lowering effect may lie outside their diuretic properties. We eva...

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Bibliografiske detaljer
Main Authors: Jessup, Jewell A., Brosnihan, K. Bridget, Gallagher, Patricia E., Chappell, Mark C., Ferrario, Carlos M.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409168/
https://ncbi.nlm.nih.gov/pubmed/19343087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jash.2007.10.005
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