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BMP4/Smad5 dependent stress erythropoiesis is required for the expansion of erythroid progenitors during fetal development

The rapid growth of the embryo places severe demands on the ability of the cardiovascular system to deliver oxygen to cells. To meet this need, erythroid progenitors rapidly expand in the fetal liver microenvironment such that by E14.5, erythropoiesis predominates in the fetal liver. In this report...

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Detalhes bibliográficos
Main Authors: Porayette, Prashanth, Paulson, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409149/
https://ncbi.nlm.nih.gov/pubmed/18374325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.01.047
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