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Nonviral Gene Delivery from Nonwoven Fibrous Scaffolds Fabricated by Interfacial Complexation of Polyelectrolytes

We investigated a novel nonwoven fibrous scaffold as a vehicle for delivery of DNA. Fibers were formed by polyelectrolyte complexation of water-soluble chitin and alginate, and PEI–DNA nanoparticles were encapsulated during the fiber drawing process. Nanoparticles released from the fibers over time...

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Detalhes bibliográficos
Main Authors: Lim, Shawn H., Liao, I-Chien, Leong, Kam W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409000/
https://ncbi.nlm.nih.gov/pubmed/16497560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2005.12.016
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