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Oocyte-Specific Overexpression of Mouse Bone Morphogenetic Protein-15 Leads to Accelerated Folliculogenesis and an Early Onset of Acyclicity in Transgenic Mice

Whereas mutations in the bmp15 gene cause infertility in ewes and women due to defects in folliculogenesis, most defects in female mice lacking bone morphogenetic protein (BMP)-15 are confined to the ovulation process, supportive of the observation that functional mouse BMP-15 is barely detected in...

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Auteurs principaux: McMahon, Heather E., Hashimoto, Osamu, Mellon, Pamela L., Shimasaki, Shunichi
Format: Artigo
Langue:Inglês
Publié: The Endocrine Society 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408818/
https://ncbi.nlm.nih.gov/pubmed/18308851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1550
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