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Vasoactive Intestinal Polypeptide Can Excite Gonadotropin-Releasing Hormone Neurons in a Manner Dependent on Estradiol and Gated by Time of Day

A surge of GnRH release signals the LH surge that triggers ovulation. The GnRH surge is dependent on a switch in estradiol feedback from negative to positive and, in rodents, a daily neural signal, likely from the suprachiasmatic nuclei. Vasoactive intestinal polypeptide (VIP) may be involved in sup...

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Главные авторы: Christian, Catherine A., Moenter, Suzanne M.
Формат: Artigo
Язык:Inglês
Опубликовано: The Endocrine Society 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408801/
https://ncbi.nlm.nih.gov/pubmed/18326000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1098
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