A 10-base-pair element of the human immunodeficiency virus type 1 long terminal repeat (LTR) is an absolute requirement for transactivation by the human cytomegalovirus 72-kilodalton IE1 protein but can be compensated for by other LTR regions in transactivation by the 80-kilodalton IE2 protein.

Ítems similars

• The human cytomegalovirus 80-kilodalton but not the 72-kilodalton immediate-early protein transactivates heterologous promoters in a TATA box-dependent mechanism and interacts directly with TFIID.
  per: Hagemeier, C, et al.
  Publicat: (1992)
• SUMOylation of the Human Cytomegalovirus 72-Kilodalton IE1 Protein Facilitates Expression of the 86-Kilodalton IE2 Protein and Promotes Viral Replication
  per: Nevels, Michael, et al.
  Publicat: (2004)
• Human Cytomegalovirus 86-Kilodalton IE2 Protein Blocks Cell Cycle Progression in G(1)
  per: Wiebusch, Lüder, et al.
  Publicat: (1999)
• Phosphorylation of the Human Cytomegalovirus 86-Kilodalton Immediate-Early Protein IE2
  per: Harel, Noam Y., et al.
  Publicat: (1998)
• Transactivation by the human cytomegalovirus IE2 86-kilodalton protein requires a domain that binds to both the TATA box-binding protein and the retinoblastoma protein.
  per: Sommer, M H, et al.
  Publicat: (1994)