High intratumoural accumulation of stealth® liposomal doxorubicin (Caelyx®) in glioblastomas and in metastatic brain tumours

The blood–brain barrier is a major obstacle for the chemotherapeutic drugs to effectively reach primary or secondary brain tumours. Stealth® liposomal drugs are highly accumulated in tumoural tissues. In the present study we investigated the relative accumulation of(99m)Tc-DTPA radiolabelled stealth...

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Bibliografiske detaljer
Main Authors: Koukourakis, M I, Koukouraki, S, Fezoulidis, I, Kelekis, N, Kyrias, G, Archimandritis, S, Karkavitsas, N
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2000
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408790/
https://ncbi.nlm.nih.gov/pubmed/11044350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1459
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