ConStruct: Improved construction of RNA consensus structures

BACKGROUND: Aligning homologous non-coding RNAs (ncRNAs) correctly in terms of sequence and structure is an unresolved problem, due to both mathematical complexity and imperfect scoring functions. High quality alignments, however, are a prerequisite for most consensus structure prediction approaches...

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Main Authors: Wilm, Andreas, Linnenbrink, Kornelia, Steger, Gerhard
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2008
Teme:
Methodology Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408607/
https://ncbi.nlm.nih.gov/pubmed/18442401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-219
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