Carbon Monoxide Protects against Ventilator-induced Lung Injury via PPAR-γ and Inhibition of Egr-1

Rationale: Ventilator-induced lung injury (VILI) leads to an unacceptably high mortality. In this regard, the antiinflammatory properties of inhaled carbon monoxide (CO) may provide a therapeutic option. Objectives: This study explores the mechanisms of CO-dependent protection in a mouse model of VI...

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Hlavní autoři: Hoetzel, Alexander, Dolinay, Tamas, Vallbracht, Simone, Zhang, Yingze, Kim, Hong Pyo, Ifedigbo, Emeka, Alber, Sean, Kaynar, A. Murat, Schmidt, Rene, Ryter, Stefan W., Choi, Augustine M. K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2008
Témata:
D. Critical Care
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408440/
https://ncbi.nlm.nih.gov/pubmed/18356564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200708-1265OC
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