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Mutations within the proteolytic cleavage site of the Rous sarcoma virus glycoprotein define a requirement for dibasic residues for intracellular cleavage.

We investigated the amino acid sequence requirements for intracellular cleavage of the Rous sarcoma virus glycoprotein precursor by introducing mutations into the region encoding the cleavage recognition site (Arg-Arg-Lys-Arg). In addition to mutants G1 (Arg-Arg-Glu-Arg) and Dr1 (deletion of all fou...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Dong, J Y, Dubay, J W, Perez, L G, Hunter, E
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240787/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1370559/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.2.865-874.1992
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