The ICP4 binding sites in the herpes simplex virus type 1 glycoprotein D (gD) promoter are not essential for efficient gD transcription during virus infection.

Activation of the early and late genes of herpes simplex virus type 1 during infection in tissue culture requires functional immediate-early regulatory protein ICP4. ICP4 is a specific DNA-binding protein which recognizes a variety of DNA sequences, many of which contain the consensus ATCGTC. In gen...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Smiley, J R, Johnson, D C, Pizer, L I, Everett, R D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240760/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1309905/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.2.623-631.1992
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