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The cell surface metalloprotease/disintegrin Kuzbanian is required for axonal extension in Drosophila

It has long been suspected that proteolytic activity associated with advancing growth cones may be required for axon extension. We have isolated mutations in the kuzbanian (kuz) gene, which is expressed in the nervous system and encodes a putative zinc metalloprotease with a disintegrin domain. Dros...

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Autores principales: Fambrough, Douglas, Pan, Duojia, Rubin, Gerald M., Goodman, Corey S.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences of the USA 1996
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC24076/
https://ncbi.nlm.nih.gov/pubmed/8917574
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