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The small RING finger protein Z drives arenavirus budding: Implications for antiviral strategies

By using a reverse genetics system that is based on the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV), we have identified the arenavirus small RING finger Z protein as the main driving force of virus budding. Both LCMV and Lassa fever virus (LFV) Z proteins exhibited self-budding a...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Perez, Mar, Craven, Rebecca C., de la Torre, Juan C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240730/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14563923/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2133782100
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