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A genetic lesion that arrests plasma cell homing to the bone marrow

The coordinated regulation of chemokine responsiveness plays a critical role in the development of humoral immunity. After antigen challenge and B cell activation, the emerging plasma cells (PCs) undergo CXCL12-induced chemotaxis to the bone marrow, where they produce Ab and persist. Here we show th...

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Detalhes bibliográficos
Main Authors: Erickson, Loren D., Lin, Ling-Li, Duan, Biyan, Morel, Laurence, Noelle, Randolph J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC240717/
https://ncbi.nlm.nih.gov/pubmed/14555759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2131686100
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