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A genetic lesion that arrests plasma cell homing to the bone marrow
The coordinated regulation of chemokine responsiveness plays a critical role in the development of humoral immunity. After antigen challenge and B cell activation, the emerging plasma cells (PCs) undergo CXCL12-induced chemotaxis to the bone marrow, where they produce Ab and persist. Here we show th...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2003
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC240717/ https://ncbi.nlm.nih.gov/pubmed/14555759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2131686100 |
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