Immunodominance among herpes simplex virus-specific CD8 T cells expressing a tissue-specific homing receptor

The study of immunodominance within microbe-specific CD8 T cell responses has been challenging. We used a previously undescribed approach to create unbiased panels of CD8 cytotoxic T lymphocyte clones specific for herpes simplex virus type 2, a pathogen with a complex genome encoding at least 85 pol...

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Autori principali: Koelle, David M., Liu, Zhi, McClurkan, Christopher L., Cevallos, Randal C., Vieira, Jeffrey, Hosken, Nancy A., Meseda, Clement A., Snow, Devon C., Wald, Anna, Corey, Lawrence
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC240716/
https://ncbi.nlm.nih.gov/pubmed/14566059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2131705100
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