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Antiviral immune responses in gene-targeted mice expressing the immunoglobulin heavy chain of virus-neutralizing antibodies

Two gene-targeted immunoglobulin heavy chain transgenic mouse strains, TgH(KL25) and TgH(VI10), expressing neutralizing specificities for lymphocytic choriomeningitis virus and vesicular stomatitis virus, respectively, have been generated. Three days after lymphocytic choriomeningitis virus infectio...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Hangartner, Lars, Senn, Beatrice M., Ledermann, Birgit, Kalinke, Ulrich, Seiler, Peter, Bucher, Etienne, Zellweger, Raphaël M., Fink, Katja, Odermatt, Bernhard, Bürki, Kurt, Zinkernagel, Rolf M., Hengartner, Hans
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240713/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14569006/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2135542100
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