A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery

Ubiquitination of membrane-associated proteins can direct their proteasome-mediated degradation or activation at the endoplasmic reticulum (ER), as well as their endocytosis and intracellular sorting. However, the full spectrum of ubiquitinated membrane proteins has not been determined. Here we comb...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Hitchcock, Amy L., Auld, Kathryn, Gygi, Steven P., Silver, Pamela A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2003
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240687/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14557538/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2135500100
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