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Positional cloning of the major quantitative trait locus underlying lung tumor susceptibility in mice

Pulmonary adenoma susceptibility 1 (Pas1), located on chromosome 6, is the major locus affecting inherited predisposition to lung tumor development in mice. We have fine mapped the Pas1 locus to a region of ≈0.5 megabases by using congenic strains of mice, constructed by placing the Pas1 region of c...

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Detalhes bibliográficos
Main Authors: Zhang, Zhongqiu, Futamura, Manabu, Vikis, Haris G., Wang, Min, Li, Jie, Wang, Yian, Guan, Kun-Liang, You, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC240671/
https://ncbi.nlm.nih.gov/pubmed/14583591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2133947100
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