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Transdominant human T-cell lymphotropic virus type I TAX1 mutant that fails to localize to the nucleus.

Human T-cell lymphotropic virus type I (HTLV-I) encodes a 40-kDa nuclear transactivating phosphoprotein, TAX1. The results presented in this study demonstrate that deletion of amino acids 2 through 59 of TAX1 (delta 58 TAX1) decreased transactivation of the HTLV-I long terminal repeat 10- to 20-fold...

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Publicat a:J Virol
Autors principals: Gitlin, S D, Lindholm, P F, Marriott, S J, Brady, J N
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240619/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2016773/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.5.2612-2621.1991
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