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Oral Direct Renin Inhibition: Premise, Promise, and Potential Limitations of a New Class of Antihypertensive Drug

The first oral direct renin inhibitor, aliskiren, recently received approval for the treatment of hypertension. This article addresses the premise, promise, and potential limitations of this new class of renin-angiotensin system inhibitor. While aliskiren adds to a list of > 100 drugs approved fo...

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Detalhes bibliográficos
Main Authors: Shafiq, Moiz M., Menon, Dileep V., Victor, Ronald G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2405917/
https://ncbi.nlm.nih.gov/pubmed/18374681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.amjmed.2007.11.016
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