Mutational inactivation of an inhibitory sequence in human immunodeficiency virus type 1 results in Rev-independent gag expression.

We have characterized an inhibitory RNA element in the human immunodeficiency virus type 1 (HIV-1) gag coding sequence that prevents gag expression. The inhibition exerted by this element could be overcome by the presence of the Rev-responsive element in cis and of Rev protein in trans. To understan...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Schwartz, S, Campbell, M, Nasioulas, G, Harrison, J, Felber, B K, Pavlakis, G N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240411/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1433510/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.12.7176-7182.1992
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