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A mutant herpes simplex virus type 1 unable to express glycoprotein L cannot enter cells, and its particles lack glycoprotein H.

Herpes simplex virus type 1 (HSV-1) glycoprotein H (gH) is essential for virus entry into cells and forms a hetero-oligomer with a newly described viral glycoprotein, gL. Normal folding, posttranslational processing, and intracellular transport of both gH and gL depend upon the coexpression of gH an...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Roop, C, Hutchinson, L, Johnson, D C
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1993
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240370/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8383241/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.4.2285-2297.1993
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