WIN 52035-2 inhibits both attachment and eclipse of human rhinovirus 14.

WIN compounds inhibit attachment of human rhinovirus 14 by binding to a hydrophobic pocket within the capsid and inducing conformational changes in the canyon floor, the region that binds the cellular receptor. To study the basis of drug resistance, we isolated and characterized a family of human rh...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Shepard, D A, Heinz, B A, Rueckert, R R
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1993
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240355/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8383239/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.4.2245-2254.1993
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