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Minimal requirements for the human immunodeficiency virus type 1 V3 domain to support the syncytium-inducing phenotype: analysis by single amino acid substitution.

The third variable domain (V3) of the human immunodeficiency virus type 1 external envelope contains determinants of cell tropism, cytopathicity, and infectivity and elicits antibodies able to block infectivity in vitro and in vivo. Our study encompassed point-mutational analysis of HXB-2 viruses co...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: De Jong, J J, De Ronde, A, Keulen, W, Tersmette, M, Goudsmit, J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1992
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240176/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1404617/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.11.6777-6780.1992
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